FAT-RELEASE AND THERMOGENESIS
Break-through research from Canadian researcher Dr. Dennis Jones on unique adrenergic
substances obtained from carefully harvested and extracted Bitter Orange has been shown to
be of interest in both fat-release and thermogenesis. Supported by the thermogenic
potential of Guarana, Dr. Jones' Advantra Z™ is appropriately balanced in STIMULEAN
with standardized herbal extracts of Suma, Gingko Biloba, Siberian Ginseng, Dioscorea,
plus Potassium, Magnesium, and Chromium Aspartates. Individuals interested in
nutritionally supporting the body's natural fat-release and thermogenic mechanisms should
consider use of STIMULEAN as part of their dietary and weight management program.
Contains no preservatives, sugar, starch, salt, wheat, yeast, milk, soy derivatives,
artificial flavoring or coloring agents.
THE BETA-AGONIST SYSTEM
The ß (beta) agonist path is a signaling pathway in the body for a number of related
areas. Many cell surfaces, especially muscle and fat cell surfaces, contain ß receptors.
When a ß agonist (or antagonist) binds to a ß receptor site, a sequence of processes are
activated that can both induce lipolysis (the breakdown and use of stored fat for energy
production) and increase muscle metabolism. The increased muscle metabolism may facilitate
muscle cell growth.
Common ß agonists already available in the body include the neurotransmitter
catecholamines-epinephrine (Adrenaline™) and norepinephrine. These agonists are
especially released during times of stress. Other materials which can interfere with the
sequence of steps in the ß agonist process include dietary materials such as caffeine,
one of the xanthines.
ADVANTRA Z™
Research conducted by Canadian researcher Dennis Jones, M.A., Ph.D. has led to the
development of a unique extract called Advantra Z™. Advantra Z is derived from the
Bitter Orange (Citrus aurantium) , also known to Chinese herbalists as zhi shi. At a
certain stage of maturity, zhi shi contains a rare composition of five adrenergic
(resembling Adrenaline™ or epinephrine) amines: Synephrine, Octopamine, Hordenine,
Tyramine, and N-Methyltyramine. Using proprietary harvesting and extraction techniques,
Advantra Z is unique in achieving a standardized content of at least 4 percent of these
adrenergic substances, which are important for their thermogenic potential. The interest
in Advantra Z lies in its ability to bind to a specific subgroup of the ß receptors
called the ß-3 receptors. The ß-3 receptors may increase the rate at which fat is
released from body stores (lipolysis), as well as increase the resting metabolic rate
(thermogenesis).
THERMOGENESIS
Thermogenesis is a term referring to the body's production of heat. Heat production is
a normal part of metabolic processes. At certain times, such as when exposed to cold
temperatures, the body may bring about an additional form of thermogenesis-shivering.
Shivering is an attempt by the body to create needed supplemental body heat by increasing
muscular activity. Certain nutritional substances can also stimulate thermogenesis.
Thermogenesis, when not simply needed for routine food digestion and metabolism, is both a
source of heat and-when stimulated through appropriate dietary supplementation-a mechanism
to increase metabolic rate. Fuel for this increased metabolic rate can be provided by
stored body fat, if released and available for use.
THE XANTHINES
Xanthines are a class of thermogenic substances found in coffee, tea and certain beans.
They are also found in animal organs. The standardized extract of Guarana (Paullinia
cupana) in STIMULEAN is a rich source of the methylxanthine, caffeine, even though the
amount contained in two tablets is less than half normally contained in an average cup of
coffee.
A SLENDER NOW PRODUCT
The STIMULEAN formulation is synergistically balanced with standarized herbal extracts
of Suma, Gingko Biloba, Siberian Ginseng, Dioscorea, plus Potassium, Magnesium, and
Chromium Aspartates. STIMULEAN is the "BURN" component in the complete Slender
Now BLOCK, BIND, AND BURN concept and approach to a rational weight management program.
STIMULEAN aids in a temporary, natural increase in body temperature and
metabolism-thermogenesis-through nutritional stimulation of the body's ß receptor pathway
which can induce the breakdown and release of stored body fat, and thereby allow stored
fats to be turned into energy. STIMULEAN brings you the thermogenesis potentials of
Guarana, of the unique and patented Advantra Z, and of a synergistic blend of supportive
herbs and minerals. STIMULEAN helps STIMU-late increased metabolism through thermogenesis,
helps burn body stores of fat, allowing a more SLENDER LEAN-er you.
